The RiboShredder™ blend is a cocktail of potent RNases that completely
degrades unwanted RNA in DNA purification procedures. This highly active
cocktail contains a proprietary, optimized blend of non mammalian RNase
enzymes. Unlike other RNase cocktails, RiboShredder RNase Blend degrades
all RNA (Fig. 1), converting RNA to nucleoside monophosphates.
Unit Definition: One unit of RiboShredder™ RNase Blend
completely degrades 130 µg of RNA in TE buffer in 10 minutes at
Assay Substrate: Nucleic acids from a standard alkaline lysis
plasmid preparation, where the RNA/DNA concentration is 13 mg/ml and
the plasmid DNA concentration is 0.5 mg/ml.